496 Miller’s Review [5 Nov 2018]

Vaccines have been thoroughly tested for safety, reactions are rare, and no published studies show vaccines cause harm. That is the position of the pharmaceutical industry, our governments, and their health organizations. But is it true?

A recent book by Neil Miller “Miller’s Review of Critical Vaccine Studies – 400 Important Scientific Papers Summarized for Parents and Researchers” (mentioned in last week's post "The Wakefield Study") summarizes research that your pediatrician or community health nurse won’t tell you about (and most likely are unaware of themselves). These studies are published in peer-reviewed medical journals and all 400 provide evidence questioning the safety or efficacy of vaccinations. Here are just a few examples.

Few studies compare vaccinated and unvaccinated populations. One such was published just last year comparing vaccinated and unvaccinated 3 to 5 month olds in the West African country of Guinea-Bissau during the introduction of DPT and oral polio vaccine in the early 1980s. The study found the death rate of all causes was a shocking five times higher in the DPT vaccinated group (keep in mind that these African infants may be malnourished and in a previously unvaccinated population so the results may not translate to North America). Previously a live measles vaccine was withdrawn after clinical trials in West Africa found that it, along with DPT, increased mortality 33% in children 4-60 months of age.

Since 1986 the American Vaccine Adverse Event Reporting System (VAERS) has received over 500,000 reports of adverse reactions to vaccinations, with 30,000 added each year. A study of this data analyzed 38,000 severe reactions (involving hospitalization or death) and found a statistically significant increase in risk as the number of simultaneous vaccines given increased, from one right up to eight.

A CDC study found that the increased risk of autism for boys getting the MMR before age 36 months was 1.69 times higher than those who got their shot after 36 months; for African American boys the rate was 3.36 times higher. The data were manipulated to hide these findings and the study concluded there was no link.

To make informed decisions about your family’s health you need all the information. This book, Miller’s website, and other resources like the National Vaccine Information Center will complement the information you receive from your doctor or health nurse.

For more information on this or other natural health topics, stop in and talk to Stan; for medical advice consult your licensed health practitioner. Find this article on my website for links to sources and further reading.

495 The Wakefield “Study” [29 October 2018]

Almost everyone has heard of Andrew Wakefield, the British gastroenterologist who wrote a fraudulent study in 1998 linking vaccines and autism. Wakefield was accused of falsifying data and having undisclosed financial conflicts of interest. In 2010 the Lancet retracted his paper and he lost his license to practice.

The conventional position is that vaccines have been thoroughly tested with no link ever found with any health problem including autism. The retraction of Wakefield’s study is considered further proof that any vaccine-autism link has been totally debunked.

But is all of that true?

First, the 1998 Lancet paper was not a “study”, it was a “case study”. A case study is merely a reporting of one or a group of patients with unusual symptoms. It does not make any claims or even propose a hypothesis. You can read the entire retracted paper here. The paper’s conclusion read “We have identified a chronic enterocolitis in children that may be related to neuropsychiatric dysfunction. In most cases [8 of 12], onset of symptoms was after measles, mumps and rubella immunization. Further investigations are needed to examine this syndrome and its possible relation to this vaccine.”

As to the fraud charges, David Lewis, a research microbiologist with the National Whistleblowers Center in Washington, reviewed Wakefield’s files regarding the Lancet paper and concluded that Wakefield had not intentionally misinterpreted the data, and that the BMJ’s fraud theory was “more tabloid news than science”. Wakefield has written a book (2010) called “Callous Disregard” in which he tells his side of the story.

In any case, the Wakefield paper is hardly the only evidence for vaccine safety concerns. A recent book by Neil Miller “Miller’s Review of Critical Vaccine Studies – 400 Important Scientific Papers Summarized for Parents and Researchers” summarizes research that you won’t find on the CDC website. Many show increasing risk of adverse reactions with vaccinations at an earlier age and with multiple vaccinations (both of which were a concern of Wakefield’s). We’ll look at some of these next week.

Whether you think Wakefield is a discredited fraud or a demonized hero, you can’t fault him for asking for more research into such an important health issue.

For more information on this or other natural health topics, stop in and talk to Stan; for medical advice consult your licensed health practitioner. Find this article on my website for links to sources and further reading.

493 The Cochrane HPV Review [15 Oct 2018]

I have previously written about bias in health science: #204 Scientifically Proven? about the built in bias in medical research; #429 Confirmation Bias and #456 Cognitive Dissonance about everyone’s bias in dealing with new information that conflicts with our beliefs; and #383 Blocking the Truth and #469 CFS – The Cover-Up about the CDCs questionable actions. So I wasn’t that shocked to read the 2015 book Vaccine Whistleblower – Exposing Autism Research Fraud at the CDC by Kevin Barry. But I was really saddened to learn of recent occurrences at Cochrane.

Cochrane (formerly the Cochrane Collaboration) is a highly renowned network of scientists from around the world that publish hundreds of meta-analyses using the highest standards of evidence-based medicine. Cochrane has maintained its very high reputation for integrity – until now.

In May of this year Cochrane published a review of the safety and effectiveness of the HPV vaccine. The human papilloma virus (HPV) is associated with (but not proven to cause) cervical cancer. The review looked at 26 studies and gave the vaccine a strongly favorable report.

In July Peter Gøtzsche, a Danish researcher, Cochrane board member, and a founder of the Cochrane Collaboration in 1993, along with two colleagues wrote a critique of the review “The Cochrane HPV vaccine review was incomplete and ignored important evidence of bias” which was published in BMJ Evidence-Based Medicine. Among the criticisms were: the review missed nearly half of the eligible studies; all of the studies selected used another vaccine as a placebo; women with a history of immunological or nervous system disorders were excluded (but are freely given the vaccine); all of the studies were industry funded; adverse effects were incompletely assessed; and serious conflicts of interest were not revealed.

The critique concluded “We do not find the Cochrane HPV vaccine review to be “Trusted Evidence” [Cochrane’s motto] as it was influenced by reporting bias and biased trial designs [and] … does not meet the standards for Cochrane reviews…”.

Instead of redoing the review to a higher standard, Gøtzsche was expelled from the board. In protest, four other scientists on the 13 man science board resigned (read their letter here).

Sadly it seems that, at least for certain health topics, there is no one left we can trust.

Sources: "Cochrane Board Expels Critic of Group's HPV Vaccine Review" Medscape 17 Sept 2018. If link doesn't work, copy and paste www.medscape.com/viewarticle/902062
"Leading Institution for Science-Based Health Advice Implodes After Industry Bias is Revealed" mercola.com 3 Oct 2018

For more information on this or other natural health topics, stop in and talk to Stan; for medical advice consult your licensed health practitioner.

469 CFS – the Cover-Up [30 April 2018]

Last week I explained how Dr. Judy Mikovits discovered a likely viral cause for Chronic Fatigue Syndrome (CFS), and I hinted at a cover-up. What happened and why?

Shortly after the publication of her 2009 Science paper, Dr. Mikovits turned her attention to autism. She became curious about a possible connection between CFS and autism when her preliminary data found a higher than expected number of children with autism among CFS patients and families. She speculated (publicly) that if children were asymptomatic carriers of the XMRV virus, a vaccination could trigger the sudden development of the disease. Retroviruses like to hide in the B and T lymphocytes, the very cells that vaccinations are designed to stimulate. This effect is well known for the HIV virus – babies born to HIV positive mothers must be treated with anti-viral drugs before their first vaccination.

In September 2011 Mikovits was suddenly fired from her position as Research Director at Whittemore Peterson Institute. A few weeks later she was arrested and her home searched (without a warrant), accused of stealing her research notebooks (which she was required by federal law to maintain and protect). She was held for five days in jail without bail or a formal charge ever being laid.

The Science study was retracted in September 2011 and an editorial was published discrediting her work (which included the police mugshot from her arrest). The CDC quickly initiated a follow-up study to confirm her findings. Mikovits protested that it was deliberately designed – in choice of subjects, handling of blood samples, and in the narrow control standard – to avoid finding a retrovirus in CFS patients. The best way to test for contamination would be to retest the same patients using her meticulous methodology, but this was not done. She was disappointed but not surprised when the studies found no correlation and concluded (erroneously she believes) that her previous study samples were contaminated. Another study had already confirmed her findings but it too was discredited and later retracted.

This raises the question: why would research institutions not want to find a viral cause of CFS? Possibly fear of public panic or class action lawsuits. But I suspect the reason is that it offers a plausible explanation for the connection between vaccinations and autism. What happened to Dr. Mikovits was, in her own words, “… a clear message to anyone in research who dared stand by data that revealed an inconvenient truth about corruption in public health.”

Sources

Book: Plague – One Scientist’s Intrepid Search for the Truth about Human Retroviruses and Chronic Fatigue Syndrome (ME/CFS), Autism, and Other Diseases. Kent Heckenlively and Judy Mikovits, 2014

Hillary Johnson, Discover magazine March 2013 Chasing the Shadow Virus

For more information on this or other natural health topics, stop in and talk to Stan; for medical advice consult your licensed health practitioner.

468 A Viral Cause for CFS? [23 Apr 2018]

Last week I described chronic fatigue syndrome (CFS) and wrote that officially there is no known cause or cure. But is that true?

In their 2014 book Plague – One Scientist’s Intrepid Search for the Truth about Human Retroviruses and Chronic Fatigue Syndrome (ME/CFS), Autism, and Other Diseases, Kent Heckenlively and Judy Mikovits tell the story of the discovery and cover-up of a possible cause (and cure) for chronic fatigue syndrome.

In 2006 Judy Mikovits, a virus research scientist with 30 years’ experience in studying HIV/AIDS, accepted a position in Nevada to study chronic fatigue syndrome. She immediately noticed several similarities between CFS and AIDS and began to suspect a viral cause. In both diseases an impaired immune system allows a wide variety of “opportunistic” infections; both have a high incidence of normally rare cancers; and both show abnormal brain scans and have similar biomarkers such as high cytokine production. Mikovits discovered a retrovirus infection in 67% of CFS sufferers and in 4% of healthy controls. She published her findings in 2009 in the prestigious journal Science.

This particular virus, called XMRV, is a mouse retrovirus, meaning that it originated in mice but had mutated and could now infect humans. XMRV had been associated with prostate cancer since 2006 (but has since been dismissed as a causative factor). The first CFS outbreak in the USA occurred in 1934-5 among the doctors and staff of the Los Angeles County Hospital after receiving a polio vaccine grown on mouse tissue. In the late 1970’s and early ’80’s pockets of CFS began showing up in cities across the country and then around the world. Today an estimated 20 million people world-wide suffer from the condition.

Patients and their families were hopeful that this discovery would lead to a cure or at least a more effective treatment. Alas this was not to be. For various reasons (to be covered next week) the medical research community turned on Mikovits, discredited her and her research, and reverted to the “no known cause” for CFS. The situation has not changed since, leaving at least one more generation of CFS patients to suffer needlessly.

For more information on this or other natural health topics, stop in and talk to Stan; for medical advice consult your licensed health practitioner.

382 Supplement Safety [15 August 2016]

Over the past year there have been several major news reports in The United States and Canada questioning the regulation, safety and efficacy of health supplements. The first was CBC’s Marketplace which reported in November 2015 that certain fish oils, vitamin C, and protein shakes did not meet their label claims. However after retesting it was discovered that the original lab tests were incorrect and there were in fact no problems with the products.

In March 2013 the US Government Accountability Office (GAO) published a report on adverse events from supplements. Since 2008 the FDA has required supplement manufacturers to report any adverse effects from their products. Between 2008 and 2011 there were 6,307 serious (e.g. requiring a hospital visit) adverse event reports (AERs) for supplements (average 1,577 a year). The same report estimated over half (68%) of Americans use supplements, so this is amazingly low from 157 million supplement users over 4 years (1/100,000 users). During the same period there were 1,736,437 AERs from pharmaceutical drugs, with fewer (only 48%) of Americans using them (average 434,100 per year or 1/253 users). In 2008 alone there were 26,517 AERs for vaccines and 526,527 AERs for approved pharmaceutical drugs.

The nature of the supplement AER’s were generally less serious than for drugs. 21% were for accidental ingestion by children (whose parents took them to the hospital as a safety precaution). Of the remaining AERs, 35% were from energy and weight loss products. Many of these contain caffeine which resulted in heart palpitations, prompting a visit to the hospital where they were examined and sent home. Deaths from supplements are very rare, less than one a year, in contrast with pharmaceuticals which kill over 100,000 Americans each year – more than from motor vehicle accidents!

While this data shows the overwhelming safety of supplements compared with drugs, I don’t want to leave the impression that supplements should be used carelessly. Balance is essential with many nutrients, especially vitamins, minerals and amino acids. Choose quality reputable brands, use only what you need, do your own research, and get advice from knowledgeable professionals.

Sources:
CBC MarketPlace documentary
GAO report
Health Impact News: GAO report critique
Mercola: Consumer Reports article critique

For more information on this or other natural health topics, stop in and talk to Stan; for medical advice consult your licensed health practitioner.

174 The Vaccine-Autism Controversy [16 July 2012]

Dr. Natasha Campbell-McBride devotes a chapter of her book “Gut and Psychology Syndrome” to the vaccine-autism controversy. I’ve been avoiding this topic for some time, but I like her balanced approach.

Autism is one of the neurological conditions (including allergies, asthma, eczema, ADD, ADHD, etc.) common in children with a compromised immune system. A child’s reaction to a vaccination depends on his or her immune health: with a healthy immune system the reaction should be normal; with a seriously compromised system it could trigger one of these conditions; with a moderately compromised system it could further weaken their immune system setting them up for some other trigger to “break the camel’s back”. On the other hand Dr. Campbell-McBride reports seeing many severely immune compromised children, who have not been vaccinated, develop one or more of these conditions. This range of reactions, I believe, explains why the connection between vaccination and autism remains controversial.

Dr. Campbell-McBride does not advocate abandoning vaccinations altogether – she recognizes that they have saved millions of children’s lives – but believes that with more and more children born with compromised immune systems, the ideal of vaccinating everyone could now be doing more harm than good. Instead she proposes a comprehensive immunological screening program – through a questionnaire and testing – to discover which children have compromised immune systems and are therefore at greater risk of severe reactions. Those most at risk* should not be vaccinated. Those with healthy parents and no particular health problems but showing some immune system abnormalities should wait until the tests improve. Only healthy infants with healthy parents and who show normal immune development should proceed with vaccinations. Even then Dr Campbell-McBride recommends single vaccines only, spaced 6 weeks apart, to reduce adverse effects.

See Dr. Campbell-McBride's website www.gapsdiet.com for more details. In the Resources tab to access articles on autism and vaccines.

For more information on this or other natural health topics, stop in and talk to Stan; for medical advice consult your licensed health practitioner.
________________

* Dr. Campbell-McBride recommends no vaccinations for infants:
• with eczema, asthma, digestive problems or any other disorder which would indicate compromised gut flora and immunity;
• born to a mother with fibromyalgia, digestive problems, asthma, eczema, severe allergies, autoimmune disorders or neurological problems;
• or having older siblings with autism, severe eczema, asthma, allergies, ADHD, epilepsy or insulin dependant diabetes.
At a later age these children can be retested and, when they show no immune deficiencies, can be vaccinated using single vaccines spaced 6 weeks apart.

023 Nutritional Therapies Ignored [4 August 2009]

The title of the book “Every Second Child” by Archie Kalokerinos refers to the 50% infant mortality rate that plagued some Australian aborigine populations in the 1960’s.

Kalokerinos, a medical doctor working in the Collarenebri district in the Australian Outback, found the Aborigine children there suffering from malnutrition caused by their switch to a “civilized” diet (white bread, jam and sausage). Combined with a lack of immunity to European diseases, the children were dying from simple upper respiratory viral infections – what we refer to as the common cold.

Kalokerinos diagnosed infant scurvy, and discovered that with a vitamin C injection, the infants rapidly recovered. He also observed that if a child was immunized while suffering from a cold, it was almost always fatal. Despite this discovery, the immunization program continued – without the vitamin C injections – and the children continued to die.

Most of the book deals with the author’s battle with skepticism, ridicule and outright hostility in trying to share his findings with the Australian medical establishment. The story is heartbreaking to read, even more so to realize that the situation is by no means an exception.

Another example, coincidentally also dealing with Vitamin C, is the successful treatment of poliomyelitis by Dr. Frederick R. Klenner of Reidsville, North Carolina. He used intravenous Vitamin C in massive doses with the 60 cases that he dealt with in his rural district during the polio epidemic of 1948. All of these cases were successful with no lasting effects. For example, two brothers that he treated completely recovered from polio and went on to become high school and college athletic stars, while their sister treated by another physician wore braces for the rest of her life.

Dr. Klenner presented a paper describing his treatment of polio with Vitamin C at the same symposium that the Salk vaccine was first announced. The vaccine attracted all the media and medical attention and Klenner’s discovery remains forgotten in some medical archive.

Why share these stories? I want to convey two ideas:

1) that there are effective and safe nutritional therapies (Abram Hoffer’s work with schizophrenia is another that comes to mind); and

2) that there is tremendous resistance to their adoption into modern health care. This resistance has little to do with science and too much with politics and economics. I see signs that this is improving, but it is frustratingly slow.

This article is intended for educational purposes only; for medical advice consult your licensed health practitioner.