August 6, 2018

483 The Placebo Effect [6 Aug 2018]


In the first few chapters of her 2016 book “Cure – a Journey into the Science of Mind over Body”, Jo Marchant explores the placebo effect.

The placebo effect is stronger and more widespread than I had realized. An enlightening example was the 1996 discovery that the enzyme secretin dramatically improved some autistic children, which when tested (in 1999) was found to work no better than a placebo. It did work, but so did the placebo (a saline injection); both groups improved significantly.

Another example is the surgical technique vertebroplasty (essentially gluing cracked vertebrae) which in a controlled study was found to be no better than placebo (a sham surgery). Again both groups improved significantly in mobility and pain relief.

So the placebo effect is more than just random improvement – there is a measurable beneficial effect due to patients’ expectations. And studies are discovering physiological changes in the body in response to these expectations which likely account for most of the favorable results. Some examples: a Parkinson’s drug placebo increases dopamine production; and a placebo pain killer increases production of endorphins (our body’s natural painkillers). Patients aren’t imagining the improvements – they are real.

The benefits of placebos are, however, limited to effects the body can control. A placebo can reduce pain, anxiety and depression, improve sleep, and lower blood pressure, but can’t replace insulin, shrink a tumor or lower cholesterol.

The author believes that any benefits from many alternative medicines and treatments like homeopathics and Reiki are due to the placebo effect. But she also reports that half of 53 surgical procedures studied in 2014, and most antidepressant drugs like Prozac, work little better than placebo. Valium for example only works if the patients know they are taking it. These drugs are still being marketed, and vertebroplasty surgery is still being performed. The author even proposes prescribing placebos, with the patients’ knowledge, in certain cases.

I’d love to see more controlled studies of natural products to learn how well they really work compared to conventional treatments. But I would still sell products that proved no better than placebo – if the customer asked for them and it was safe to do so. Why not harness the power of the mind to improve our health?

For more information on this or other natural health topics, stop in and talk to Stan; for medical advice consult your licensed health practitioner.

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